This article on Epainassist.com has been reviewed by a aesculapian professional , as well as checked for facts , to insure the readers the best possible truth .
We follow a strict editorial insurance and we have a zero - tolerance insurance policy regarding any level of plagiarism . Our article are resourced from reputable on-line varlet . This article may contains scientific reference . The numbers in the parenthesis ( 1 , 2 , 3 ) are clickable links to compeer - reviewed scientific papers .
The feedback link “ Was this Article Helpful ” on this pageboy can be used to account content that is not precise , up - to - date or questionable in any way .
This article does not provide aesculapian advice .
There are so many people hold out in America who suffer from at least one pelt problem . There are some that many of us have listen of , such as rosacea , eczema and acne , and chances are that you yourself might be suffering from one of them .
There also survive a wide spectrum of uncommon tegument diseases , which you never knew existed , ranging from mild to fatal . In some patients , these rare skin condition affect their quality of aliveness so naughtily that they are ineffective to officiate .
Let ’s talk about these relatively unheard of cutis diseases .
Harlequin Ichthyosis(1, 2, 3)
verbal description : Harlequin ichthyosis is a uncommon genetic disorder of the tegument where children are carry with thick and toilsome skin , which looks like scales shaped like adamant across their consistence .
Symptoms : These graduated table are divided by deep cranny and can affect the shape of the patient ’s ears , eyelids , nose and lip . This rarified skin disease can also throttle the motion of the chest and tree branch .
suit : Up till now , about 200 cases of Harlequin ichthyosis have been reported all over the world . The cause of Harlequin ichthyosis is a mutation in the ABCA12 gene that is creditworthy to make a vital protein to let the skin cell to develop normally . This transmitted chromosomal mutation hinders motion of lipids to the top layer of the pelt and causes development of plates which see like scales . These scales make trouble in : push any infection ; managing the temperature of the body and cope the loss of pee .
Diagnosis : This transmitted skin upset is an autosomal recessive disorder that ’s egest on via genetic mutation . transmissible testing needs to be done to empathise who are at endangerment for inherit this as biological carriers seldom show symptoms .
discourse : Treatment for harlequin ichthyosis is the use of skin - repairing moisturizers and hide - softening emollients . unwritten retinoids are prescribed for severe typeface of harlequin ichthyosis .
Hidradenitis Suppurativa(4, 5, 6)
Description : Hidradenitis suppurativais a pertinacious , farsighted terminus instigative pelt disease , characterise by development of lesions on component part of the soundbox where skin meet peel . Some of the common places for the lesion of Hidradenitis suppurativa breakouts are : breast , underarms , upper thighs , posterior and groin .
causal agency : The cause of Hidradenitis suppurativa is not clear , but the character of hormones is suspect in the maturation of the lesions , as this status usually begins around the time ofpuberty .
Risk Factors : Who gets this disease is guess to depend on factors such as resistant system and genetics . Around 2 % of the universe suffers from Hidradenitis suppurativa . This condition is more usually escort to occur in individual who smoke or are obese . Females are at three times more danger for this disease than males for developing Hidradenitis suppurativa .
symptom : The start symptoms of Hidradenitis suppurativa resemble boil or pimples . The lesions can stay on the pelt , can clear up and reappear . If Hidradenitis suppurativa is not process , then the severeness of the symptoms increases and additional symptom educate , such as : contagion , scar and lesions that rupture and free a foul - smelling fluid .
complication : the great unwashed suffering from hidradenitis suppurativa are more susceptible for developing certain problems or comorbidities like : type 2 diabetes , acne , squamous prison cell carcinoma;inflammatory bowel disease;polycystic ovarian syndrome ; follicular closure foursome and metabolic syndrome .
Cure and Treatment : Hidradenitis Suppurativa has no remedy ; however , there are various treatment option to ease and finagle the symptoms and these are : hormone therapy , topical ointments , anti - inflammatory drug and in terrible cases , surgery .
Morgellons Disease(7, 8, 9)
Description : This is another rare skin disease , which not many knew existed characterized by small atom and vulcanized fiber and out of pelt sore , resulting in a cringe sensation on the tegument . These lesion can be seen on the extremities , trunk and the question .
preponderance : Not much is known about Morgellons disease ; however , according to the Morgellons Research Foundation it seems to have affected more than 14,000 family .
causa : Some expert think that Morgellons disease is a psychological job as the symptoms of this condition resemble delusional infestation , which is a mental health shape .
risk of infection ingredient : midway - age bloodless woman abide more from Morgellons disease and this skin term is also unite withLyme disease .
symptom : Symptoms of this disease cause pain , but this rarefied peel disease is not fateful . Some of symptoms of Morgellons disease are : depression;fatigue ; anxiousness ; itchy skin sores / rash ; inglorious stringy like material within and on the skin .
Treatment : As there is no clean understating of Morgellons disease , there is not clear cut intervention for this rare skin disease . citizenry stand from Morgellons disease is advised to keep in touch with their doctors and get discourse based on their symptoms .
Inverse Psoriasis(10, 11, 12)
Description : Also known as intertriginous psoriasis , Inverse psoriasis look like Hidradenitis suppurativa where there is formation of violent lesions on the areas where skin gather hide . These lesions are smooth and shiny in appearance .
Prevalence : About 3 % of people all over the world are affected withPsoriasisand 3 to 7 % percent of these the great unwashed have opposite psoriasis .
grounds : patient suffering from inverse psoriasis often suffer from at least one other form of psoriasis on other parts of their consistence . The exact cause of psoriasis is not clear but resistant system and genetic science are thought to be the primary contributing factors .
symptom and Treatment : The tegument present in high - friction areas , where the skin gets rubbed against tegument is tender and for this reason treatment becomes challenging . Topical ointment and steroid creams are prescribed , but if they are used excessively , then can cause further terrible botheration . For severe caseful of reverse psoriasis , treatment can consist of injectable biologics and ultraviolet B ( UVB ) light therapy for managing this rare skin disease .
Elastoderma(13, 14, 15)
Symptoms : Elastoderma is yet another unheard of skin condition where the affected role has increase elasticity or dissolution of the skin on some specific parts of the body lead in sagging and hanging of the pelt in loose , saggy folds . Elastoderma can develop on any area of the body ; however , the extremities and the neck more so and around the human knee and human elbow are the most affected surface area of the soundbox .
Cause and preponderance : Elastoderma is see in lesser than 1 in 1,000,000 individuals all over the world . The cause of elastoderma is not yet been indentified . This skin stipulation is thought to occur because of extravagant production of elastin , which is a protein responsible for providing geomorphological supporting to tissues and reed organ .
Treatment and Cure : Elastoderma has no remedy and there is not right intervention for this rare skin consideration . Surgery is chosen as treatment option by some patients to strike the loose skin portions ; however , this saggy skin commonly comes back after the surgery too .
Pilonidal Sinus Disease(16, 17, 18)
Description / symptom : This uncommon skin disease causes the ontogenesis of small tunnels or holes at the fold or the al-Qaeda of the buttocks . The symptom of this cutis disease are not always detectable and this is the rationality why many patients do not look up doctor or even substantiate that they are suffer from this disease until prominent symptoms develop .
causal agent : Pilonidal sinus disease develops when there is rubbing of the pilus present between the derriere . This imperativeness and friction push these hairs inward and make them ingrown .
risk of infection Factors : Pilonidal venous sinus disease is seen to occur in 10 to 26 the great unwashed out of 100,000 people . Many patients suffering from this unheard of peel disease are often between the ages of 15 and 30 . Men seem to suffer double more from this tegument disease than cleaning woman . This pelt disease commonly affects individuals who have sedentary jobs which need them to sit for tenacious hours at a time . Pilonidal venous sinus disease is also a co - morbidity of hidradenitis suppurativa .
discourse : address an infected pilonidal venous sinus is done calculate on certain factors , such as : the abscess size of it ; the patient role ’s symptoms and if this is a recurring transmission or a Modern transmission . Treatment consists of draining the infected pilonidal sinus along with the usance of topical ointments , red-hot compresses and antibiotic drug . If you suffer from fall back abscesses , then it is important to confer your physician about other operative options .
Cutaneous Crohn’s Disease(19, 20, 21, 22, 23, 24)
Description and preponderance : Crohn ’s diseaseis a known disease , which cause firing of the gastrointestinal parcel of land . Around 780,000 people in America support from this disease with about 38,000 new cases developing every yr .
lawsuit : Experts think resistant system , genes and the environment are creditworthy for the growing of Crohn ’s disease . About 20 to 30 % patients suffering from Crohn ’s disease suffer from outbreak of tegument lesions and this is refer to as a cutaneous eruption .
symptom : Cutaneous lesions from Crohn ’s resemble genital warts and fall out after the intestine term has manifested on the skin or another organ present outside the GI tract , such asgallbladder , liver , eyes and even joint too .
Cure and Treatment : Crohn ’s has no cure . operating theater is the master line of intervention for cutaneal wound . If there is spreading of the Crohn ’s and its lesion , then it can cause lot of pain and cause life-time threatening complications . There are very few treatment pick for address this condition as of now .
Pemphigus Vegetans(25, 26, 27, 28)
Description and Cause : Pemphigus vegetans is classify as group of autoimmune diseases , by the National Institutes of Health , which make yourimmune systemattack your good for you mobile phone of the epidermis , which is upmost layer of the skin . Just like in hidradenitis suppurativa , the blister or lesions in Pemphigus vegetans develop where the skin naturally rubs or partake together along with acquire on the : venereal areas , nose , mouth , eyes and pharynx .
Prevalence : Pemphigus vegetans is a character of pemphigus vulgaris and affects about 1 to 2 pct of all the pemphigus patients all over the world .
Treatment : If Pemphigus vegetans is not cover , then it can become life threatening . Treatment consists of removing the blister or wound and preventing them from recurring . Steroids are the first production line of treatment for lowering the inflaming . Treatment for lesions in the throat and sassing consist of medicated gargle or a corticosteroid know as clobetasol for regale unwritten problems . Other than medications , patient can opt for surgery to remove bleb / lesions along with cleansing and bandage the area every day .
Sneddon-Wilkinson Disease(29, 30, 31)
Description : This cutis disease is characterized by development of pus filled wound in clusters on the skin . Sneddon - Wilkinson diseaseis also known as sub - corneal pustular dermatosis .
Cause : The cause of this disease is not well-defined and this condition is normally misdiagnosed due to it being so rare . Sneddon - Wilkinson disease usually affects womanhood over the old age of 40 .
Symptoms : As consider in hidradenitis suppurativa , in this condition too there is formation of bump with pus inside them between the sphere of the skin that gets rubbed together a lot . The cutaneous lesions of this condition form between the skin folds on the torso and venereal area and due to the detrition they break open assailable . Along with the popping of these excrescence , patients also experience burning and itching aesthesis too . These are follow by discoloration and scaling of the skin . Sneddon - Wilkinson disease is painful and continuing ; however , not life threatening .
Dowling-Degos Disease(32, 33, 34)
Description : Dowling - Degos disease is a skin condition resulting from a genetic disorder , and causes darken of the hide , peculiarly in areas where the skin folds , such as the joint areas , jetty and armpit . The changes of the pigment also affect the scalp , hands , brass and neck ; however , this is less common .
Symptoms : Many of the lesion of Dowling - Degos disease look like blackheads ; however , there can be evolution of some acne like red spots around the oral fissure . These lesions can also arise on the scalp as protuberance fill with fluid . patient role can also feel burn and itching in these lesions of Dowling - Degos disease .
This rare skin disorder run to hap in early adolescence or late puerility . However , some individual can have the lesion of Dowling - Degos in the adulthood too . This skin condition is not fatal ; however , patients do suffer from anxiety and distress over this disease .
remedy and Treatment : There is no curative for Dowling - Degos and treatment consists of topical steroid , optical maser therapy and retinoids with varying results and not necessarily effective .
Inverse Lichen Planus Pigmentosus(35, 36)
Description : This skin disorder is an incitive disease characterized by itchy and discolored and bumps in the fold of the skin .
preponderance : About 20 case have been reported all over the earth and Inverse lichen planus pigmentosus seems to affect citizenry from Asia more .
Cause : The cause for Inverse lichen planus pigmentosus is not known .
symptom : The lesions of Inverse lichen planus pigmentosus are flat discolored macula , which develop in clusters . These lesions often do not have pus in them , but they can have though . There are some patients whose skin naturally exonerate up as prison term buy the farm on ; whereas many patients have persistent symptom for many years .
Treatment : Inverse lichen planus pigmentosus is not a sprightliness threaten status and treatment is done using topical corticosteroids for healing and in some cases this handling help oneself with pigmentation also .
Conclusion
There is no doubt that having a skin problem / disease of any type is tough on a individual emotionally , physically and psychologically . One should confer with your doctor and get treatment accordingly for loyal results . The veracious skin doctor will discover out the cause of your symptoms and come up with the good treatment plan for wangle and treating your cutis condition .
reference :
