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Topic Overview
Amyotrophic Lateral Sclerosis or ALS which is also known by the name of Motor Neuron Disease and Lou Gehrig ’s disease is a apace reformist neurodegenerative condition in which the upper motor neuron of the brainpower and the lower motor nerve cell of thespinal cordget regard . This result in the individual experiencing severe weakness and muscularity wasting away thereby affecting the overall mobility of the person . As the condition progresses the person then starts throw trouble with swallowing , speech , and breathing . finally , the affected role has respiratory loser within three years of diagnosis and in most cases succumbs to the condition.[1 , 2 , 3 ]
According to estimation , about 30,000 people in the United States have aluminium with approximately 5000 cases being diagnose every year . The root cause of ALS is not yet known but enquiry suggests that both environmental andgenetic factorsmay be at play in the exploitation of this condition . There is no remedy for ALS as of yet and treatment are basically supportive and palliative.[1 , 2 , 3 ]
The treatment for atomic number 13 are place to prevent tortuousness and make the life of the patient as easier as potential . It involves a multidisciplinary approach involving mixture of specialists including strong-arm , speech and occupational healer , nutritionist , social workers , psychologists , and hospice care . However , there is one study that has been print in The Lancet which states that a dieting high on carbs and Calorie has a inclination to slow down down the progression of ALS.[1 , 2 , 3]This article goes into more detail as to whether high carbs and calories really slow up down the advance of ALS .
Can A High Calorie and High Carb Diet Slow The Progression Of ALS?
Since job with run through and swallowing are some of the primary symptoms of ALS , muscle and fat loss is quite common during forward motion of the disease . However , a research team from the Massachusetts General Hospital in Boston have discover in an animal field of study that mice that were overweight or obese and had ALS had better luck of survival for long period of time than mice which were not heavy . This prompted the researchers to get whether certain dietary modifications like diet plenteous in carbs and large calorie impact the progression of ALS in humans.[3 ]
For this , the researchers take 20 patient who were diagnose with advanced ALS and were already dependent on PEG subway system feedings . These participants were separate into three groups . The first chemical group was then put on a gamey carb and high calories dieting . The second grouping was fed with high avoirdupois and high calorie diet and the third group act as a control group and was give dieting to hold weight.[3 ]
The affected role were ask to come after this diet approach pattern for a period of a month and were monitored for five months from the study service line . After cautiously analyzing the data after the study , the research worker found out participants in the control mathematical group had 42 adverse events related to ALS and participants who were on high-pitched carb and high kilocalorie diet had only 23 untoward events and none of them were serious or fatal.[3 ]
Another reflexion made by researcher was that the group that was on high carb and high calorie dieting gained about 0.39 kilogram in free weight every calendar month compare to only 0.1 kilogram per calendar month in the ascendance group . It was also observed that there was an average weight loss of about 0.46 kilo in the group on high-pitched avoirdupois and high kilogram calorie dieting . The researchers also observed that there were no adverse consequence as a solvent of weighting gain note in any of the groups throughout the study.[3 ]
The lead investigator Dr. Willis commented on the determination that even though the sample size was quite modest the results are extremely affirmative about whatever results they observed during the field and the results are consistent with whatever observations that were made in the animal study with gamy carbs and gamy calorie dieting amend the survival to a certain degree.[3 ]
Dr. Willis suggest this physical body of nutritionary treatment can be a novel path to slow down the progression of ALS and may also be useful for treatments of other neurological conditions . However , the researcher admit that the sample size was very lowly and studies need to be done on a much larger universe to better infer the link between in high spirits carbs and gamey kilogram calorie diet and progression of ALS.[3 ]
An editorial pertain to the field of study written by Dr. Ammar Al - Chalabi of King ’s College London states that despite the result of the study he may not change the dietary plans in his affected role with ALS but he is extremely interested in the outcome of studies that are done on a much turgid population . He mentions that Dr. Willis has taken a large leap in finding a non - pharmacologic handling that is easy to administer and is well tolerated by all patients.[3 ]
He states that more enquiry needs to be done on a much larger ordered series to complete the body of work that the squad of researchers from Massachusetts General Hospital in Boston have initiate on the complex topic of dietary intervention and ALS disease progression.[3 ]
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