This article on Epainassist.com has been reviewed by a aesculapian master , as well as checked for facts , to assure the reader the well possible accuracy .

We succeed a strict editorial policy and we have a zero - tolerance insurance regarding any level of plagiarisation . Our articles are resourced from reputable online page . This article may hold in scientific references . The number in the aside ( 1 , 2 , 3 ) are clickable data link to compeer - review scientific newspaper .

The feedback link “ Was this Article Helpful ” on this page can be used to describe subject that is not precise , up - to - date or confutative in any manner .

This article does not provide aesculapian advice .

Approximately 25 % of parvo B19 infection are asymptomatic.(1 )

Arthropathy tie in with B19 infection is more common in females than in males.(2 )

Can Parvovirus B19 Infection Cause Lupus?

Although parvovirus B19 infection does not cause lupus , it may mimic the clinical presentment of systemic lupus erythematosus and confuse the clinicians into reaching a correct diagnosis . Parvovirus B19 infection is associated with a transitory autoimmune state that with serologic and PCR testing shows the front of autoantibodies , in about 25 - 68 % of the cases . The antibody present include rheumatoid factor , antinuclear antibodies , phospholipids , and antibodies to double - stranded desoxyribonucleic acid , Sjogren ’s syndromeantigens A and B , and ribonucleoprotein . The resoluteness ordinarily takes post within 3 months of the infection.(1 )

Clinically , acute parvovirus B19 infection can also be distinguished fromsystemic lupus erythematosusas the distinct feature of SLE that admit the malar rash call for the nose is absent in parvo B19 contagion . Other distinguishing features of B19 contagion include soft symptoms , and absence seizure of alopecia , discoid lesions , and Raynaud ’s phenomenon . The intimacy of the heart , kidney , GI piece of land , spleen , brain , eye , and persistence of febricity is rare in B19 contagion . Anemia consort with parvovirus B19 infection is due to pearl marrow crushing ; whereas , inlupus , it is due to autoimmune hemolysis . The reticulocyte count is low-pitched in B19 infection ; whereas normal to high in lupus . Mainly , the course of B19 infection is ego - limiting whereas lupus is a chronic disease and symptoms persist throughout life.(1 )

Does Parvovirus B19 Cause Joint Pain?

Generally , parvovirus B19 infection is asymptomatic in around 25 % cases . The manifestations of symptomatic infection let in erythema infectiosum ( fifth disease ) , arthropathy ( joint disease ) , transient aplastic crisis ( TAC ) , bone marrow nonstarter , and foetal disease ( in meaning women).(1 )

The most mutual presentation of parvovirus B19 infection is erythema infectiosum , which is mostly seen in children . It is relate with prodromal symptom offever , nausea , unease , moth-eaten , headache , and muscle pain . It is followed by a red macular or maculopapular rash on the impertinence with associated circumoral pallor . The ‘ slap cheek ’ visual aspect of the efflorescence is commonly insure in children . The rash may be fidgety and can overspread to the torso and lower body . The rash may go back or aggravate due to sun exposure , stress , or exercise . This rash is commonly ego - limiting and subsides on its own.(2 )

In adults , this rash is associated with polyarthropathy syndrome in which they develop acute symmetric arthritis that regard belittled joints . charwoman are more commonly affected ( about 60 % ) than men ( about 30 % ) . The most commonly affected spliff include joints of the hands , knees , wrist , feet , and ankles . Arthropathy may admit pain in the neck and/or swelling in the joints that are usually harmonious . However , unlikerheumatoid arthritis , arthropathy associated with parvo B19 infection is not associated with erosion of the joint and is not chronic . In most case , there is a complete resolving power of the joint disease in a few weeks.(1),(2 )

Although parvo B19 infection is non - sinister for sizeable individuals , it may become life - threatening for immunocompromised patients and foetal infection during pregnancy . Patients with blood disorders and mellow cherry roue cell dollar volume may see a transient aplastic crisis .

Immunocompromised affected role may suffer from red cell aplasia and bone heart suppression . enate contagion may precede to edema fetalis or intrauterine foetal death . The mortality associate with fetal infection is around 15 % before week 20 of gestation.(1 )

Parvovirus B19 Infection

Parvovirus B19 is a single - stranded deoxyribonucleic acid virus belonging to the family Parvoviridae . It is the first - ever known virus in its family to infect humans . It is an extremely common transmission worldwide . In honest-to-goodness adults , the antibody seropositivity pace reach 90 % from 5 - 10 % in tiddler of 2 - 5 year of eld . The infection is more usual in school going children and is transmitted to the family via them . The transmission is seasonal with a peak in late winters and former spring . The transmission is principally via respiratory droplets , female parent to child , and blood and blood production . In healthy somebody ’s parvo B19 is associated with an passing down mortality rate.(1),(2 )

References :

Also take :