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Crizotinib- This is a drug approved by the FDA in 2011 for treatment of lung cancer . Some study have shown that presidency of Crizotinib for treatment oflung cancerhas make kidney combat injury in individuals.1In this clause , we will discuss about how does this drug piece of work , its potential side effect and how does it impress the kidney resulting in kidney injury . In this article , we will also talk over a typesetter’s case subject field , which virtually provesCrizotinibas being responsible for for acute kidney injury .
What Is Crizotinib and How Does It Work?
What Are The Side Effects Of Crizotinib or Kinase Inhibitor?
Common Side Effects of Crizotinib or Kinase Inhibitor
Less Common Side Effects of Crizotinib or Kinase Inhibitor
Rare Side Effects of Crizotinib or Kinase Inhibitor
How Does Crizotinib or Kinase Inhibitor Affect The Kidneys?
What Do The Studies Say About The Relation Of Crizotinib or Kinase Inhibitor with the Kidneys?
Kidney Toxicity: Crizotinib or Kinase Inhibitor Causing Kidney Injury
This is a vitrine of an someone with innovative non - small - cell lung cancer who was treated with standard treatments of cisplatin , bevacizumab andchemotherapy , but the Crab was not able-bodied to be controlled.4Upon value the cancer cell ALK cistron mutation was identified . Crizotinib was then started on this individual . When the intervention with Crizotinib started the renal purpose of the soul was normal but with the governance of Crizotinib there were two occasions where the serum creatinine horizontal surface of the someone was found to rise importantly along with macroscopic hematuria . At that time , a nephritic biopsy was performed identifying acute tubular necrosis , which pointed to a recent renal affront or injury . These renal trauma were extremely tight related to to the presidential term of Crizotinib , which potentially affirm the function of Crizotinib in Acute Kidney Injury .
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