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What is Cyclopia?
Cyclopia is an extremely rare chance variable of holoprosencephaly , a innate disorderliness , which is characterized by failure of the eyes to be part into two orbits equally at the clip of parentage . This means that child with Cyclopia are born with only one eye which is locate at the center of the os frontale . This is the most severe form of holoprosencephaly.[1,2 ]
The rarity of this condition can be analyse by its incidence rate which is about 1 in 100,000 birth . Another feature of Cyclopia is the absence of the olfactory organ . In legal age of the case females with an conceptus that has Cyclopia have still births or self-generated abortion . Cleft palateand tooth abnormalities along with hormonal unbalance and genital abnormality are some additional features that are seen in baby with Cyclopia.[1,2 ]
What Causes Cyclopia?
What exactly causes Cyclopia still stay unknown but there are several risk divisor for this experimental condition . These include genetics , gestational diabetes , infection while significant , overexposure to ultraviolet light during maternity , alcoholand recreational drug employment during pregnancy.[2 ]
The National Institute for Rare Disorders states that chromosomal abnormalities are an important factor in the development of holoprosencephaly of which Cyclopia is a variance of . It is trisomy 13 , meaning the fetus has three copy of chromosome 13 , which is responsible for for holoprosencephaly and Cyclopia.[2 ]
How Is Cyclopia Diagnosed?
Cyclopia develops within the first 18 to 28 days of pregnancy . The lineament of Cyclopia can be seen with a regularultrasoundof the fetus during the evolution stage itself . Additionally , visualize in the form ofMRI scanscan also be used to make a diagnosis of Cyclopia.[2 ]
What Is The Life Expectancy For A Child With Cyclopia?
The prognosis of a child with Cyclopia is extremely poor . In fact , majority of the cases of Cyclopia are either stillbirth or the female has a self-generated abortion . At maximum , infants with Cyclopia survive for a maximum of a few hour . There is no cure or handling for Cyclopia . Treatment only center on providing life documentation and addressing other symptoms.[2 ]
In summary , Cyclopia is the rarest and the most extreme form of holoprosencephaly . It is seen in 1 out of 100,000 parentage . Trisomy 13 is believed to be the cause behind development of holoprosencephaly . babe with Cyclopia will have characteristic features of a single eye in the midpoint and absence of the nose along with extra genital and tooth abnormalities.[1,2 ]
Cyclopia get during the first trimester of pregnancy , within the first month . Most cases of Cyclopia finish up with either spontaneous miscarriage or still birth . The survival rate of infant with Cyclopia are very low of just a few hours . The condition is so uncommon that even parent who carry this hereditary trait very rarely give giving birth to an infant with Cyclopia.[1,2 ]
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