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Paraganglioma can affect people of any age but mostly comes between the old age of 30 to 50.(1 )
How Dangerous Is Paraganglioma?
The severeness and the risk belonging to the dangerousness of paraganglioma depends upon various factors . Paraganglioma is usually a benignant tumour which does not present commonly till the eld of 30 and can show up between 30 to 50 years age group.(2)Paraganglioma is basically of two eccentric depending upon the cell mental object present in it . It can be of a parasympathetic eccentric which is usually located at the skull base near the foramen Magnum and the cranial nerve figure 9 and 10 located near it . It may sometime also be engaging them . Another type is the sympathetic case in which there is a output of proteinaceous hormone known as catecholamine .
These types of paragangliomas are very diagnostic and in about more than 50 % of showcase , it can bring out adrenaline hormone and its related symptom like flushing of the facial expression , increasedblood pressure , palpitation , headache , hunky-dory tremors , etc . These can become dangerous and also can be living - threatening if the blood pressure is very high because it can conduct to various other complications of eminent bloodline pressure like a ruptured intracranial aneurysm , aortic dissection , left ventricular bankruptcy , etc .
Some of the paragangliomas can get converted to metastatic tumors which breaks off and goes to different web site in the body . They keep on producing the hormones and also cause of multiple pipe organ dysfunction . The prognosis is very poor when it gets commute to a metastatic transformation . Even after the surgical handling of such tumors , there are gamy chances of recurrence and become life - threatening in the closing .
benignant paragangliomas are most usually treated with surgical intervention and have a very favorable prognosis . But in some type , like in casing of parasympathetic paraganglioma , the tumor is associated with the skull nucleotide and can be in close neck of the woods or encase various cranial nerves like the glossopharyngeal , vagus , etc . In such case , the surgery itself becomes a very complicated procedure and can lead to various complicatedness associated with the intraoperative and postoperative period . It has to be done under a brain surgeon with bully precision and accuracy otherwise it can leave to the expiry of the someone intraoperatively . But if the neoplasm is lying in a non - life - threaten position then it can be operate very easily and the prognosis becomes successful.(3 )
Is Paraganglioma Contagious?
Paraganglioma is a neoplasm formed of unnatural neurons arising from neural crest cellphone and these are mould due to genetic aberrations , abnormality in the bm of such cells , malignant transformation due to some external causes , etc . There is no known infectious or inflammatory cause responsible for the paraganglioma . It is noncontagious and can not spread out from one person to another via any bod or method whatsoever . Many rumors have been spread about its transmissible nature but all are sham .
Conclusion
Paraganglioma itself is a benign tumour and does not express a very bad prognosis and has a very rare chance of malignant translation . But in some typesetter’s case , the emplacement of paraganglioma becomes very of import because it may be difficult to surgically resected the tumor from such a location even if it is benign . In such cases , the prognosis becomes very poor and sometimes surgery has to be rule out from the option .
It is not communicable as this tumor does not uprise from an infected cell - the likes of in other cases where there is the development of Cancer from the virally infect cells because they can also alter the genetic makeup of a cellphone and force it to produce a neoplasm .
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