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The resistant system of the body is to protect the consistence from foreign particles and organism . As before long as the foreign particle enter the body , our resistant organization becomes active and destroy the molecule or being . Sometimes , the immune system procedure abnormally leading to the fire on its own tissue paper and cell . The cells get damaged leading to disruption of physiologic use . Myasthenia gravis is also an machine - immune disease .
How Does A Person Get Myasthenia Gravis?
Autoimmune – Our resistant arrangement is the basal defense of the body . Whenever any foreign particles aggress our consistence , the immune organization gets aerate and the strange subatomic particle or organism gets kill by the synchronize function of the cells of the resistant system . However , in some cases , the disease is caused due to the attack of the immune organization on the body ’s own healthy tissue and organ . The disease make due to the damaging essence of the immune organization is make love as an autoimmune disease .
Myasthenia gravis is also an autoimmune disease . Various acetylcholine receptors are present at the neuromuscular junction . Acetylcholine is a neurotransmitter that helps in the effective functioning of the muscles by bind to its sense organ . In myasthenia gravis , the resistant system of the body attacks the sensory receptor of acetylcholine , leading to a reduced number of sites for binding acetylcholine . It lead in fewer nerve sign to contact and relax the muscles leading to muscle weakness.(1 )
genetic science – Although a non - inherited disease , various research worker consider that the condition is make due to variations in certain genes that trigger off the attempt of the resistant system on acetylcholine receptors leading to myasthenia gravis . It has been incur that in most of the case , myasthenia gravis occurs in families with no story of this condition . It has also been found that the gene genetic mutation of the autoimmune characteristics may also increase the risk of other autoimmune diseases such asSystemic Lupus Erythematosus.(2 )
Thymus Glands – Thymus secretor is a part of the immune organisation and is also believe to the contributing element for the maturation of myasthenia gravis . This is due to the fact that in not of the case of myasthenia gravis , the thumb gland is enlarged . In some case , thymomas , a tumour of the genus Thymus secretor , is also present . The thymus gland is believed to trigger or bring about the antibodies that moderate to myasthenia gravis.(3 )
Other Reasons – Although the presence of myasthenia gravis antibodies is the hallmark for diagnosis of the myasthenia gravis , almost 10 % of patients do not have myasthenia gravis antibodies . Such type of myasthenia gravis is known as seronegative myasthenia gravis . The symptoms of both types are standardized , and the seronegative myasthenia gravis is diagnosed through the forcible symptoms and through the answer to discourse .
Myasthenia Gravis Risk Factors
malady – During illness , the body becomes inactive which leads to an increased in the severeness of myasthenia gravis . Viral infection triggers the symptoms of myasthenia gravis .
tension – Stress , both strong-arm and excited , contributes to the progression of myasthenia gravis . Thus , strong-arm accent should be avoided , and mental stress should be managed .
Fatigue – Myasthenia gravis is characterise by impuissance of the muscles . Fatigue increase the severity of the condition .
Other Factors – Various other factors that increase the risk of development of myasthenia gravis are environmental factors , smoking , alteration in sexual activity hormone and exposure to pathogen .
Conclusion
Myasthenia gravis is an autoimmune disease but the precise cause for abnormal behavior of the immune system of rules is not exactly known . Other causes for myasthenia gravis admit thymus abnormality and genetics . In some cases , there is an absence of antibodies . Various risk factor such as tiredness , sickness , and accent also chip in to the progression of myasthenia gravis .
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