Connective tissue paper disease is the grouping of diseases that mold connective tissues of the consistence such as skin , blood , etc . It causes lighting of the protein rule in the connective tissue . These protein are elastin and collagen . Elastin is found in ligaments and skin that helps in stretching like a gum elastic band . Collagen is found in skin , cornea , rakehell , blood vessel , gristle , tendon , and os . This protein binds the cells together .
How Does Connective Tissue Disease Affect The Body?
Connective tissue disease causes inflammation of these proteins and affects their connexion with aligned organic structure parts or pipe organ . Women are more affected by them than man . Connective tissue disease affects hide , muscle , juicy , blood , blood line vessel , tendons , ligament , bone , gristle , centre , heart , lungs , kidneys , and even GI tract . This can be understood in the following ways-
Skin – this disease can get inflammation of the skin , make them thick , fragile and less stretchy . Scleroderma , arthritic arthritis , systemic lupus , polymyositis , etc . are the types of connective tissue disease that dissemble the skin . In epidermolysis bullosa , the tegument is so faint thatblistersor tears seem in the skin even with the rubbing of clothes .
Eyes – it cause dryness of the eyes ( Sjogren ’s syndrome ) and abnormal positioning of the heart lens system ( Marfan syndrome ) . In osteogenesis imperfecta , aristocratical or gray tint appear in the gabardine of the eye .
Blood And Blood Vessels – it affects blood and blood vessel . It causes inflammation of the blood vessels that can touch on the menstruum of blood to various organs and tissues of the torso . In vasculitis , stock watercraft get inflamed . InEhlers - Danlos syndrome , the blood vessels are weakened .
Muscles And Tendons – the connective tissue paper disease weaken the muscleman and sinew . It may also glower down the muscle deal due to collagen irregularity . It is seen in osteogenesis imperfecta and polymyositis .
castanets , Cartilage , Ligaments , And Joints – connective tissue paper disease get inflammation of bones , cartilage , ligaments , and joint . Immune organisation sometimes attack bones , cartilage , ligaments and synovial membrane around the joints like in rheumatoid arthritis . In systemic lupus erythematosus , osteogenesis imperfecta , etc , they are affected .
Lungs – this disease may induce accumulation of fluid in the lung chair to curtness of breath ( occurs in SLE ) . Rheumatoid arthritis , it may lead to the organization of nodules in the lungs . It may also induce lung scarring and injuries to blood vessels of the lungs as seen in dermatosclerosis . This causes breathlessness and shortness of breath . In polymyositis , muscles of lung are dissemble lead to deep intimation and cough .
Heart – aorta gets flesh out in Marfan syndrome eventually leading to its break . affection valve also get inflamed due to Marfan syndrome and other connective tissue disease go center problems .
Gastrointestinal Tract – it is affected most in epidermolysis bulbosa resulting in its symptom . in Sjogren ’s syndrome , digestion problems are increase due to lack of secretion of juices in the GIT .
kidney – the muscle of the vesica are strike in epidermolysis bulbosa . Blood rate of flow is affected in vasculitis and other connective disease .
A connective tissue disease is a group of disorders characterized by kindling and damage of protein found in the . Two protein namely collagen and elastin get affected that do a variety of job in various reed organ . Its causal agency are unclear . Genetic predisposition , autoimmune responses , and others may trigger this disease . It affects skin , bones , cartilage , ligaments , tendon , joint , eyes , digestive piece of ground , lungs , and mettle . The incendiary changes of these protein make inflammation , fluid buildup and slow harm of these reed organ , lead various serious problems . Its symptom involve discredited skin , teetotal eyes , shortness of intimation , painful joints and many more .
Conclusion
Connective tissue disease as the name advise causes job with connective tissue leading to various problems . It is because of lighting , and retrogression of the muscles , bones , roue and blood vessel . It affects various organs of the dead body as discuss above .
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