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Diabetes:-Diabetes appears when the physical structure ’s blood glucose ( a chief source of energy and comes from the food that you rust ) level is elevate . It ordinarily mention to Diabetes Mellitus and lead to severe legal injury to various organs like the heart , descent vessels , optic , kidney , and nerves over metre . Type-1(insulin - dependant or childhood - onset ) and Type-2(adult - oncoming or noninsulin - dependent ) diabetes are the most plebeian among all diabetes type . Other eccentric of diabetes are Gestational Diabetes , Diabetes Insipidus , Monogenic diabetes , etc . 90 - 95 % of all diabetic affected role are oftype-2 diabetes.1,2
In the 21st C , diabetes is the truehearted growing planetary wellness exigency . accord to the work , it is judge that about 463 million people had diabetes worldwide in 2019 , and this number is visualize to reach 578 million by 2030 and 700 million by 2045 . The World Health Organization considered diabetes an epidemic and predicts that it will be the seventh big reason of death worldwide soon.3,4
In this article , Section-1 will discuss current available treatments and problem associated with type-1 and type-2 diabetes . Section-2 will discourse the future of diabetes with specific focus to various target areas on which the research worker is working to cure diabetes .
Section 1: Currently Available Treatment For Diabetes
SECTION 1.1 : Type-1 Diabetes : – Insulin with little - do , steady act , intermediate - acting , and long - dissemble dose range is used nowadays for type-1 diabetes treatment . Other than this , Immunotherapy , Metformin , Blood gelt drug , Cholesterols drugs and Aspirin , etc . are the uncommitted treatment.5
trouble with current therapy for handle Diabetes Type 1 : – These therapies are only act against the event that happen due to disease . These therapy have no role in really preventing or altering the pathophysiology of the disease . The master goal in plow diabetes involves the bar or decreasing rate of the autoimmune process of beta - cell destruction .
incision 1.2 : Type-2 Diabetes : – Treatment admit Metformin , Sulfonylureas , Meglitinides , Thiazolidinediones , DPP-4 Inhibitors , SGLT-2 Inhibitors , GLP-1 Agonist and Insulin , etc.6
The Problem Associated With Current Therapy For Treating Diabetes Type 2 : – Most of the drug therapies useable for type-2 diabetes are only to control the diabetic shape and not heal the disease . Every drug used in Type-2 diabetes discourse has some side effect and affects various organs in the long term . For model , Sulfonylureas have side effects such as weight gain and hypoglycemia . Kidney complications are associated with Metformin . Thiazolidinediones may cause weight addition , liver disease , and swelling of stage or ankles .
Section 2: The Future Of Diabetes Treatment: Is Cure Possible?
Whatever will be brought by the future tense will undoubtedly make a Brobdingnagian difference in million of lives worldwide . scientific discipline strain to find a diabetes intervention that can heal this chronic disease , but the question remains the same “ How closely are we ? ” The biotech industry is look at it as an chance and depend to grow young diabetes intervention to cure this chronic disease . Let ’s look at the bodily function going on in this domain and how those activities will alter diabetes treatment.7,8
SECTION 2.1: Type-1 Diabetes
Some companies are also working on gene therapy , combination therapy , etc . but most of the trials are on their earlier phase.9
SECTION 2.2: Type-2 Diabetes
SECTION 2.3: Type of Surgery to Cure Diabetes
Conclusion:
Diabetes is a chronic disease that is increasing with an alarming preponderance charge per unit worldwide . The universe health organization is also believe as epidemic disease and predicting that it will be the seventh most cause of deaths worldwide .
Researchers are working on various advanced engineering and new mechanisms for discover the cure for Diabetes . It ca n’t be said how close we are to the treatment of diabetes . Most of the clinical trials are in the early level , but the future ca n’t be predict because some of the previous studies did not show in effect responses with the same approach path as now are give out on .
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