Is Lichen Planus an Autoimmune Disease?
Lichen planus is a T - cell mediated autoimmune disease . The T - cells key the normal cell in the hide and mucose membranes of various part of the body as incorrect jail cell . Therefore , the thyroxine - electric cell activate and ruin these cells . This will have the lesion in the consistency . It mainly come about in the unwritten cavity . Other than that it also occurs in the skin , genital tract , nails , ears , scalp , oculus and gorge . Lichen planus ( LP ) is a continuing inflammatory disease that affects the skin and mucous membrane . It is an autoimmune disease . It is seen in many region of the body . Commonly see in the unwritten cavity . Other place lichen planus go on are pelt , genitals , ears , nail . Lichen planus pass off when the immune scheme attacks the cells on the skin and mucose membrane .
Pathophysiology of Lichen Planus
The resistant system in your body is divided into acquired and the natural immunity . unconditioned immunity is the immunity we all are born with . This include the hide and mucous tissue layer which are the innate barrier . This immunity is general and non - specific . If the pathogen is able to pass this barrier then the acquired immunity activates and attempt to put down the pathogen . As the name implies acquire immunity is something you grow throughout life . When you are exposed to disease / pathogens ( antigens ) the body protects it and produce antibody ( reception to the antigen ) this will protect you from further attacks forge the same pathogen . When you get vaccinate also your soundbox make antibodies and protect you forge that disease . This is the acquire immunity . acquire unsusceptibility is further divided into T - cell resistance and B - cadre immunity . In autoimmune disease the acquire resistant arrangement attacks the normal cell name them as pathogens or faulty cadre . There are many autoimmune disease and lichen planus is one of them . Lichen planus is a T - cadre mediated autoimmune disease . T - cells triggers death in normal cells identifying these jail cell as faulty cells . This autoimmunity gives upgrade to the wound .
Where Does Lichen Planus Occur?
Oral Cavity – lichen planus mainly occurs in the oral cavity . It includes the cheeks which is the common locating in the unwritten dental caries . Then it ’s also seen in the tongue , gums , palate , and in the inner side of the lips . The lesions appear as
Skin – purplish lesion that are raise form the tegument Earth’s surface . These lichen planus lesions are itchy .
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