interracial connective tissue disease is a reform-minded disease and symptom in most of the patients worsen with meter . Management strategies of this experimental condition are available , but the disease also causes mortality due to various complication . Risk factor include age , grammatical gender , family history and other autoimmune diseases in the patient role .
Is Mixed Connective Tissue Disease Fatal?
Mixed connective tissue disease is a biography - threatening precondition and the risk of fatality further increases when the symptoms are more of systemic sclerosis or polymyositis . The fatality may be due to pulmonary arterial hypertension , thrombocytopenic peliosis , cardiovascular conditions , and systemic transmission . Even the treatment to retard the term is usable but the disease is progressive , and the symptom worsen with time .
A with child telephone number of people have their symptom aggravate in a point of 6 to 12 yr . Although various complications are make due to mixed connective tissue disease , a large numeral of fatalities occurred due to pulmonary arterial hypertension . The presence of the mark i.e. Immunoglobulin G ( IgG ) anticardiolipin argue the bearing of pulmonary hypertension . The risk of cardiac complicatedness further increased due to the presence of antiphospholipid antibodies . Pericarditis is the most often occur cardiac complication in mixed connective tissue disease .
The patient who dies also lose from other complications such as esophageal hypomotility , malignity , and serositis . It has been found that this disease is more mutual in adult female than in men . It is also to be noted that ruffle connective tissue for not scale down the aliveness expectancy except in cases where the condition has tortuousness such as pulmonary high blood pressure , or heart disease .
Mixed Connective Tissue
motley connective tissue is a rare , continuing autoimmune disorder whose symptoms overlap with the three diseases i.e. systemic sclerosis , Systemic Lupus Erythematosus , and
Polymyositis . Thus this condition is also known as lap syndrome . The condition which is suppose to be causing the disease include hyperactive immune reply , thymine - lymphocyte activating , vascular endothelial proliferation and hyperactivity of Beta - lymph cell . Some patients also develop anti - Sm auto - antibodies within a few days after the diagnosing .
These affected role are more prostrate to developing interstitial lung disease and the risk of infection of developing skin sclerosis decreased in these affected role . U1 small atomic ribonucleoprotein 70 kDa is a protein present in the homo . Antibodies against the sherd of this protein are the primary cause of miscellaneous connective tissue disease . absolute majority of the patient stick out from this stipulation develop Raynaud ’s phenomenon . The symptoms of this phenomenon are excessive chemical reaction to cold and the fingers of the patient become blue or purple . Other symptom of this mixed connective tissue disease includefatigue , fever , weakness , joint painand skin disorders . The severity of the symptom vary from patient role to patient .
Risk Factor Of Mixed Connective Tissue Disease
Various factors increase the risk of motley connective tissue paper disease . These factors include :
Gender . charwoman are importantly at higher risk for develop mixed connective tissue disease . The proportion of occurrence of this condition in women and world is 3.1 to 16.1 .
eld . Although sundry connective tissue disease can take place at any long time , generally the people at the years compass of 15 year to 25 years are at in high spirits risk .
sept History . Although there is no conclusive grounds to show that people with a family history are more prostrate to develop mixed connective tissue paper disease , various researches bespeak that there might be a genetic component involved as this disease commonly rule in those multitude who have a home history of this disease .
Any Other Autoimmune Disease . sundry connective tissue paper disease is a inveterate , rare autoimmune disease . Autoimmune disease is the condition in which the immune organization of the consistence starts damaging its own cells . Thus , the person suffer from any other autoimmune disease such as hypothyroidism is at eminent risk for developing this status .
Conclusion
Various complications take place due to miscellaneous connective tissue paper disease . This may go to fatal implications and death of the affected role may occur . Pulmonary arterial hypertension is the main cause of death . Pericarditis is the leading grounds of deaths due to cardiovascular tortuousness . The patient role may also die from systemic infections .
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