This clause on Epainassist.com has been brush up by a aesculapian professional , as well as checked for fact , to assure the reader the well possible accuracy .
We accompany a rigorous editorial policy and we have a zero - tolerance insurance policy regarding any level of plagiarism . Our articles are resourced from reputable online pages . This article may contains scientific references . The numbers in the aside ( 1 , 2 , 3 ) are clickable link to peer - survey scientific papers .
The feedback link “ Was this Article Helpful ” on this page can be used to report content that is not exact , up - to - date or questionable in any manner .
This clause does not provide medical advice .
Clinical study show that the rapid spread of infections can lead to the diversification of viral infections.1,2
Human parvovirusB19 infectionsare commonly mild and symptomless that do n’t require discussion however when there are symptom , analgesics and febrifuge are used to excuse complications.3
Although there is no specific antiviral drug to take in the infection alternate treatment like blood transfusion , anti - inflammatory drug , and intravenous immunoglobulin are recommended.4
Is Parvovirus B19 A Progressive Infection?
The clinical display of parvo B19 contagion motley widely ranging from meek symptoms to life - peril severe tortuousness . When the bed cover of the infection is rapid , it typically tolerate the reformist diversification of viral isolates . The non - synonymous diversification is broadly enhance indicate the vigorous effect of the virus which in turn accounts for the uniformness of the biological conduct .
The pathogenesis of human parvovirus is complicated and varying , and this structure conduce to the progression of neurological manifestation . The main target area cubicle of this virus are erythroid primogenitor cell in the bone marrow . It is a progressive stipulation and can be propagated to a limited extent in human bone marrow cells .
A study was acquit on two patient role cover bone bone marrow abnormalities , progressive ataxia , and tremor who were aged 27 months female and 13 years male person . These patient report acute contagion however after worthy treatments , they recoup bit by bit in two twelvemonth with no further treatment of ataxia .
Although in some cases , recovery was completely achieved , event , where complications are severe morbidness , was observed.1,2
Alternative Treatments For Parvovirus B19
Parvovirus B19 A is typically asymptomatic so self - care treatment at home is sufficient to plow this condition . However , in some cases , ramification can be serious . For case , patient with severe anemia will require hospitalization insurance forblood blood transfusion . Some of the alternative handling for parvo B19 infection admit
line of descent blood transfusion – This is a workaday aesculapian routine during which the donated blood is infused into your body through a minute electron tube placed in the vena . This is considered as a life - bring through procedure during surgery or injury where there is a severe rakehell expiration . parentage blood transfusion is most appropriate for parvovirus patient suffering from severe anemia.3
Anti - incendiary drug – When the temperature rise more than 102 F , Acetaminophen / Tylenol may help facilitate temperature . They are also helpful in still underage aches and pain sensation .
Intravenous Immunoglobulin - Medical theory states that IVIG therapy has bring about examine results for parvo B19 - associated consummate RBC aplasia in immunosuppressed individuals and patients with dogged parvovirus contagion . This theory is a powerful pecker to meliorate patient condition and to deal the infection . More recently intravenousimmunoglobulintherapy is used as a potential treatment against cervical and pancreatic carcinomas.4
In September 2007 in the United States , the National Institute of Allergy and Infectious Diseases initiated a recombinant human parvovirus B19 vaccinum . study expect that this vaccinum can be helpful briefly to prevent immunodeficiency .
work in the past showed that human parvovirus is a gun trigger ofnephrotic syndrome . The HPV B19 is associated with significant morbidity in patient role with sickle cell disease . It is more common in children when compare to adult .
The affected role affected with this virus shows symptom after 14 days of contagion . A bright red rash also called a slapped cheek rash is a classic symptom of human parvo and a recognized feature of the 5th disease .
References :
Also Read :
