Latex is a substance get from the sap of the Hevea tree brasiliensis . In its production process is add dissimilar substances count on the want final characteristic .
Diagnosis of Latex Allergy
The clinical history guide by the specialist provides very utilitarian entropy . The presence of other allergies , atopy , surgeries and endangerment groups , potential beginning of exposure , episodes of urticaria andanaphylaxisare collected , as well as possible reactions in telling to the consumption of plantain , Actinidia deliciosa , avocadoandchestnut .
The complemental diagnosing is found in skin run ( prick or intraepidermal test ) and purpose of specific IgE ( blood test ) .
Is there a Blood Test for Latex Allergy?
What blood tests or testing ground test are usually done to study the allergic reaction ? – In an supersensitized reaction , unlike cells ( lymphocytes , mast cells , basophil , eosinophil … ) and multiple molecules take part , some of them specific to the allergen that trigger the chemical reaction ( antibodies or immunoglobulins ) and other substances that mediate the allergic reply , common for the different allergen ( histamine , tryptase , etc ) . The science lab techniques available for the diagnosis of allergy are to psychoanalyze the specific reaction , trying to identify the responsible allergen for the patient ’s symptoms ; and , on the other bridge player to determine the immunological mechanism of the allergic reaction . depend on the fraction of blood in which these test are do , techniques can be sort into two : serologic and cellular techniques .
The serological technique are performed in the affected role ’s blood serum , that is , in the parentage fraction that remains once the mobile phone and some proteins that are involve in coagulation are removed . This fraction contains the immunoglobulins or antibody , and other substances called mediators of the allergic chemical reaction , such as histamine or tryptase , among others .
On the other hand , the cellular techniques applied to the diagnosis of allergic reaction are carried out using the in vitro study as the substrate , the effecter cells of the allergic reaction sequester from the peripheral blood of the patient role , lymphocytes and/or basophile ; and observing its activation after in vitro stimulation ( in a trial tubing ) with the suspected allergen .
Provocation Test : They are point when the story is implicative and the completing tests are negative or contradictory , or to rule out latex allergy in affected role who do not have symptoms .
The most used is the glove utilisation test , in which a glove finger is first reach and then a full glove , using a vinyl group or nitril glove as a negative control on the other handwriting ; it is reckon positive if the patient presents erythema , pruritus , bleb or respiratory symptoms .
It can also be performed the incitation trial run bronchial specific by aerosolise particles of rubber-base paint either from an sedimentary excerpt or by agitation of powdered glove , although in children its use is very restricted .
Is it Essential to perform Blood Tests once the Skin Tests are done?
While it is rightful that peel tests are cheap and well-off to perform , bloodline examination in allergology provide additional information that complements the diagnosing in vivo in most case . In fact , the determination of specific IgE has a greater specificity than skin tests , in such a manner that with the cutaneal tests it is potential to choose a large numeral of patients , among which the honest allergic ones would be included , but also some of them that are not really ( false positives ) , and that with the conclusion of the IgE they are identify in a high-pitched percentage . In this direction , the combination of both tests increase diagnostic carrying out .
In addition , while skin tests are not quantitative , the determination of specific IgE actually is . It is important to remark that a big size of the wheal receive in the pelt tryout is not always related to a higher level of specific IgE.
Conclusion
Later allergic reaction is not common and its diagnosing is sometimes a challenge . hide examination are complemented by blood tests , although on those occasions when they are not indicated – either by take away drugs that interfere with them or by the presence of hide problems- , bloodline run will be the only type of diagnosis useable to the doctor .
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