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What is Myxedema Coma?
Myxedema coma is a complication of advancedhypothyroidismand is also known as a myxedema crisis . It is the release of brain function due to long - standing low thyroid gland internal secretion levels . It is a aliveness - threatening complication .
Hypothyroidism is a consideration in which the thyroid is not capable to develop enough thyroid hormone.(1)The hormones produced by the thyroid are triiodothyronine ( T3 ) and T ( T4 ) , which bring a role in regulating several functions in the body , including:(2 )
Lack of T3 and T4 cut off body functions and leads to myxedema coma .
What Causes Hypothyroidism?
There are many conditions that may moderate to hypothyroidism , including :
Patients with myxedema coma have a account of hypothyroidism thyroid surgical procedure and radioactive I intervention for the thyroid . In rare cases , the condition is not due to the inability of the thyroid secretory organ but due to the failure of the pituitary secreter , or the hypothalamus to send correct signals to the thyroid gland to work normally . Here the thyroid gland gland is normal but is not sending or receiving proper signals to make the thyroid gland endocrine , it is capable of producing .
Contributing Factors of Myxedema Coma
There are a few contributing factors that may trigger myxedema comatoseness . These include:(3 )
It is crucial for those with hypothyroidism to hear and keep warm . Also , a doctor should be confabulate if any contagion is taking longer than usual to get treated .
Symptoms of Myxedema Coma
Myxedema coma go on when the body is not able-bodied to tolerate the symptoms of hypothyroidism and the symptoms admit :
How is Myxedema Coma Diagnosed?
A doctor can appraise the level of T4 in the body to diagnose myxoedema coma . quick endocrine replacement is started which is based on the symptoms , even before the result comes . The symptom admit :
More tests are performed to mold the thyroid gland function and other status affect the thyroid gland .
Treatment of Myxedema Coma
The main treatment involves giving the patient breathing treatment and helping him warm up . Antibiotics are started to heal the infection .
patient with hypothyroidism without myxedema are treat with T4 endocrine , but in the case of myxedema coma , the treatment is dissimilar . If myxedema comatoseness is suspect , hormone substitute therapy is started to facilitate the symptoms by restoring the T3 and T4 hormone level . Normally T3 is a hormone that is metabolically active and is produced by the thyroid gland gland . In patients with no job , T4 is converted into T3 in the bloodstream . In those with myxedema coma , the patient is so macabre that this conversion is impaired . In such cases , T3 is bulge initially followed by T4 therapy as well .
Depending on the advancement of comatoseness T3 and T4 internal secretion are administered using a dribble . Oral treatment is yield if the person is well enough to take it . Additionally , other medication including steroids are move over .
How to Prevent Myxedema Coma?
The primary path to cope myxedema coma is to foreclose this status from occurring . The doctor should be visited regularly for observe - up and blood tests to determine the dose is appropriate .
Anyone with symptom that touch on them , should visit a doctor to talk about the headache and search the treatment options for hypothyroidism . If the treatment is started early most people with myxedema coma have a positive lookout . Without rapid diagnosis and handling , the stipulation can show to be fatal .
