Pemphigoid is a rare type of autoimmune upset commonly impact the elderly masses ; however , it can affect person of any years too . Pemphigoid is characterized by skin blister and rashes on the sleeve , legs , and abdominal cavity caused due to malfunction of the immune organisation . There may also be blistering of the mucose tissue layer of the nose , eyes , mouth and vagina . This can also occur in pregnancy . As of now , there is no cure for pemphigoid , but the prognosis of pemphigoid is good with discussion . Many affected role do good with treatment and in many cases the disease will go away after some years of treatment . However , there are some patient where even with diligent treatment , there is return of pemphigoid .
discussion comprises of negociate this disease and its symptom with practice of medicine , such ascorticosteroids , immune suppressant drug and certainantibiotics .
Types of Pemphigoid
There are different types of pemphigoid and they all hap as a answer of malfunction in the immune system . Patient develop rashes and fluid - fill blisters on his / her skin . Depending on the location and the time of the growing of the blizzard and blister , the unlike type of pemphigoid are :
Causes and Risk Factors of Pemphigoid
Pemphigoid is an autoimmune disorderliness where our physical structure ’s resistant system , instead of protecting us frominfection , mistakenly starts attacking its own level-headed tissue . In pemphigoid , the immune organization bring out antibodies which attack the hypodermic tissue paper , which is present beneath the peel ’s outer bed . This results in breakup of the layers of skin and leading to blistering and rashes which are very dreadful . The precise crusade behind our immune system of rules behaving this way is not known .
There are some spark off factor for this condition , such as certainmedications , ultraviolet light therapy , radiation therapy etc . Individuals who already are suffering from otherautoimmune disordersare more prone to develop pemphigoid . This precondition also largely affects the elderly mass .
Signs and Symptoms of Pemphigoid
The primary symptom of pemphigoid is the water filled bulla which uprise on the stomach , arms , legs and mucous membrane . The blister have the next characteristic :
Investigations for Pemphigoid
Physical examination of the blisters is often sufficient for a diagnosis . For classic diagnosing , exam such as biopsy , where small cutis samples of the affected regions is removed and sent to lab for examination , is done . These biopsied samples are examined for immune organisation antibody , which are present in pemphigoid . ancestry tests can also be done , as these antibodies can also be found in the blood .
Treatment for Pemphigoid
There is no lasting cure for pemphigoid , but discussion can greatly relieve the symptom .
