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What is Retroperitoneal Fibrosis?
Retroperitoneal fibrosis is a condition in which excess hempen tissue paper develops in the retroperitoneal area in the body , which is a space behind the stomach and gut .
Fibrosis is the emergence of excess connective tissue that take to the organisation of hoi polloi . This compress and block the ureter , the tubes that bear urine from the kidney to the bladder .
The tissue paper mass can block either one or both the ureter . As the water endorse up in the ureter , the harmful fabric enters the blood and damages the kidney . It can lead tokidney failureif not addressed early .
Retroperitoneal fibrosis starts with the inflammation and fibrosis of the abdominal aorta , a large arteria that brings blood from the heart to the area below the kidney . As the disease progresses the arteries carrying bloodline to the leg and kidney get affected . This leads to pain , leg swelling , and a diminution inkidney single-valued function .
What Causes Retroperitoneal Fibrosis?
The cause of retroperitoneal fibrosis remains unknown in two - third of cases.(1 )
Age and gender are the principal hazard factors as it is screw to occur more between the ages of 40 and 60 and happen twice as often in men as in women.(2 )
The conditions associate with retroperitoneal fibrosis include :
Retroperitoneal fibrosis can also be affiliate with :
Symptoms of Retroperitoneal Fibrosis
In retroperitoneal fibrosis , there is a drop-off in the line flowing from the aorta to the lower part of the body .
In the early stages of Retroperitoneal fibrosis when the eubstance react to reduced blood catamenia , symptom are :
As the disease progresses the symptom of Retroperitoneal fibrosis include :
It is authoritative to see the doc forthwith as the urine output lessen along with abdominal and humbled back pain .
Complications of Retroperitoneal Fibrosis
The complications related to Retroperitoneal fibrosis vary harmonize to the size of it and placement of the spare growing . It can consequently induce wrong to the expanse served by the abdominal aorta .
The swelling and blockage of the ureter if not treat can lead to serious trouble such as chronic kidney failure , recollective - term blockage of ureters . This can further lead to urine back - up and kidney tumefy .
Untreated retroperitoneal fibrosis can run to cut off the blood provision to the legs that have grievous ramification .
Diagnosis and Treatment of Retroperitoneal Fibrosis
CT scanandMRI scanare need for an accurate diagnosing of Retroperitoneal fibrosis .
Additional test include :
handling for Retroperitoneal fibrosis depend on the hardship and location of the fibrosis . In the former stage anti - inflammatory medications , corticosteroids , and immunosuppressants are order .
After the fibrosis has obstruct one or both of the ureters , the doctor needs to empty the obstruction . For this , the urine has to be run out with the aid of a stent or drain pipe that is stick in through the back into the kidney .
In some cases of Retroperitoneal fibrosis surgical process would be require to :
If diagnosed and treated at early stages the long - condition outlook of Retroperitoneal fibrosis is very good . In the case where kidney equipment casualty is minimal and surgery is successful , there are 90 percent chances of retentive - term success.(3 )
In severely affected case , damage can be lasting and there can be a need for a kidney transplantation .
