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Myelodysplastic syndrome ( MDS ) is a type of cancer in the bone marrow which is the principal site of hematopoiesis . Bone marrow squash produce stem cell which differentiate into maturedred blood prison cell ( RBC),white blood cell ( WBC)and platelets . In myelodysplastic syndrome these stem electric cell rise into unnatural cells called dysplastic cubicle and bang cells which are immature root prison cell . So , there are not any mature healthy rakehell cells in the blood which precede to symptom such asanemia , recurrent contagion , and bleeding disorders ; most myelodysplastic syndrome progress into acute myeloid leucaemia ( AML ) .
What Are The Different Types Of Myelodysplastic Syndrome?
There are many assortment system , World Health Organization ( WHO ) classifications are the used widely , and it classifies myelodysplastic syndrome according to their appearance microscopically along with some other feature .
The features are :
Myelodysplastic Syndrome With Excess Blasts (MDS-EB)
This case the patients have more blow cells in the os gist and/or blood , more dysplasia in cells and at least one mobile phone character is very low in number .
Myelodysplastic Syndrome With Ring Sideroblasts (MDS-RS)
Many of the early RBC are ring sideroblasts and the diagnosing is made when 15 % of other RBC are ring sideroblasts or if 5 % of cell have an irregularity in the SF3B1 gene . Divided into two based on the number of cell types show dysplasia
Rare type of myelodysplastic syndrome seen ordinarily in aged char ; for an unsung reason , these patient have a good prognosis and seldom shape up into AML
Myelodysplastic Syndrome, Unclassifiable (MDS-U)
It is a rare character and characteristic do not match any other type of myelodysplastic syndrome.(1 )
Conclusion
There are many classification method acting of myelodysplastic syndrome , WHO categorisation is commonly used where it classifies MDS agree to their appearance microscopically along with some other feature . There are 6 types myelodysplastic syndrome with multilineage dysplasia ( MDS - MLD ) which is the coarse type , myelodysplastic syndrome with unmarried descent dysplasia ( MDS - SLD ) , MDS with excess blasts ( MDS - EB ) most probable to progress into AML , MDS with ring sideroblasts ( MDS - RS ) , MDS with disjunct del(5q ) , and myelodysplastic syndrome , unclassifiable ( MDS - U )
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