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Multiple endocrine neoplasias are the inherited disease of overactive ductless gland gland that may run in crime syndicate . It is due to the transfer of mutate or defective cistron from parents to children . The defective cistron stimulate overproduction of hormones by one or more ductless gland gland in the affected person at the same time . It may involve endocrine secretory organ like a parathyroid gland , pancreas , pituitary , thyroid , and adrenal gland . This disease can be diagnosed through a blood line test ; genic testing , CT scan , andMRI scan . It can not be heal and its symptom can be get by .
What Are The Symptoms Of Multiple Endocrine Neoplasia?
Multiple endocrine neoplasia syndrome or MEN refers to a group of inherit disorders that leads to the development of tumour in more than one tumour in hormone glands at a time . It can involve major endocrine secreter like pituitary , thyroid , parathyroid , adrenal , and pancreas . The tumour affect the levels of the hormone secreted by these glands . The tumour developed can be benign or malignant . Benign tumour are slow - develop tumors that are located in a individual part of the eubstance and do not spread to other part . It is also not a life - jeopardise consideration . Malignant tumors are rapidly develop tumors that circularise to other parting . If malignant tumors are not manage decent , it can be black .
The symptoms of multiple endocrine neoplasia syndromes depend on the type of MEN . It also depends on the affected endocrine system . This impress the secernment of internal secretion in the trunk that may cause dissimilar symptoms.(1 )
The types of multiple endocrine neoplasia are-
MEN 1
It usually touch pituitary , parathyroid , and pancreas . It can develop at any age and may develop in men and charwoman both . It commonly has a kinsfolk history of the condition.(3 )
Symptoms-
MEN 2A
It involve adrenal secreter , thyroid gland gland , and parathyroid gland . Its symptom break due to the formation of tumors . It break at the eld of 30 years.(2 )
MEN 2B
It affects specifically adrenal secreter and thyroid gland . Its symptom involve-
Multiple Endocrine Neoplasias Causes
Multiple endocrine neoplasias are the inherited disease that seem due to mutation of the genes transferred from the parent to the children . The gene are defective that are meant to carry information for a protein nominate menin . This ensue in the visual aspect of neoplasm in various endocrine glands in the same person . MEN II is induce by a bad cistron known as RET . This defect can appear in the affected individual and can cause the development of many tumors not always at the same metre .
This disorder can educate at any age and affects both males and females equally . This disease is seen in families and passed from contemporaries to coevals . Those who have a family history of MEN are at more risk of grow this disease .
Conclusion
Multiple endocrine neoplasia are the familial circumstance that leads to the organisation of tumors in the endocrine gland secretor in the same individual usually at the same time . Its symptoms representation is consort to its types . Its symptoms involve anxiety , bony abnormality , weakness , mental changes , visual damage , and many others discussed above .
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