Autoimmune disease occur when there is an attack on dead body ’s own electric cell by resistant arrangement . Generally , immune organization assist body fight extraneous bodies / infection such as viruses , bacteria and fungus , but due to various factors such as genetic science , age and environment the immune organization bring forth antibodies against its own cells .
There are over 80 identified autoimmune disease and the examples of mutual autoimmune disease includelupus , Sjogren ’s syndrome , Grave ’s disease , rheumatoid arthritis , inflammatory bowel disease , Hashimoto ’s thyroiditis , vitiligo , psoriasis , case 1 diabetes , multiple sclerosisandMyasthenia gravis . Either these pathogens ( mostly bacteria and virus ) lead to autoimmunity due to damage of resistant organization or there is output of certain elements by pathogens that resemble the host cells due to which resistant arrangement also aggress normal host cells due to its resemblance to foreign cells .
What Infections Cause Autoimmune Diseases?
The Most Common Autoimmune Diseases Associated To Infections Include :
-Type 1 diabetes is tie in with coxsackievirus B4 , cytomegalovirus ( CMV ) , mumps , and rubella computer virus .
-Rheumatoid arthritis is associated with Epstein Barr virus ( Epstein-Barr virus ) , hepatitis C computer virus , mycobacteria and Escherichia coli bacteria .
-Multiple sclerosis is relate to infection by Epstein Barr computer virus , cytomegalovirus and measles virus .
-Lupus is consort with Epstein Barr virus .
-Guillain - Barre syndrome is thought to be because of Epstein Barr computer virus , cytomegalovirus and Campylobacter bacteria .
-Myasthenia gravis is tie in with herpes virus simplex virus and hepatitis C virus .
-Myocarditis is associate with Chlamydia bacterium , CMV and coxsackievirus B3 .
Epstein Barr Virus
EBV is a very mutual contagion and go to herpes virus family of viruses . It do glandular febrility / mononucleosis . It is call back to be a trigger for about 33 different autoimmune diseases . Epstein Barr virus is linked with the development of rheumatoid arthritis , multiple induration , Guillain - Barre syndrome , systemic lupus erythematosus and Sjogren ’s disease .
Cytomegalovirus
This computer virus also belong to the family of herpes virus virus and is an highly common contagion . Patients are usually symptom less when infected with this computer virus , so they are incognizant of their stipulation . With imperfect immune system , symptoms such as sore pharynx , meek fever and mild hepatomegaly are present . Cytomegalovirus increases the risk of develop case 1 diabetes , myocarditis , multiple sclerosis and Guillian - Barre syndrome .
Herpes Simplex Virus
This computer virus is associate with herpetic stromal keratitis ( HSK ) that may lead to blindness . HSK symptom are alleviated by immunosuppressants , thus indicate involvement of immune arrangement . However , most of the study are done in murine sample distribution due to difficulty in studying in humans .
Coxsackievirus B
This virus is mostly associated with infectious myocarditis as viral RNA has been isolated from patients heart . However , these are study in infected mice and there is uncertainty about the disease pathology in homo . Coxsackievirus B is also associated with developing autoimmunity in type 1 diabetes .
Streptococcal Infection
Streptococcal infection is a very common contagion , mostly associated with streptococci pharynx that has symptom of painful throat , febrility and cervical lymphadenopathy . Although , sore throat is a viral transmission , but patients can have secondary streptococcus bacterial infection . Strep infection is also associated with rheumatic fever autoimmune disease that involves joint ( arthritis ) , heart ( myocarditis ) , skin ( rashes ) and wit ( Sydenham chorea in which there is unvoluntary movement of facial muscles , arms , legs and trunk ) . Streptococcus is also take a trigger for autoimmune glomerulonephritis , Tourette syndrome and pediatric autoimmune neuropsychiatric upset affiliate with Streptococcal infections ( PANDAS ) .
Helicobacter Pylori
H. pylorus is associated with increased risk of exposure of stomach ulceration and stomach Cancer . It is mostly found in bowel and leads to gastritis causing symptom ofheartburn , bloat , nausea , stomach painand burp . This bacterium is connect with rheumatoid arthritis , psoriasis , systemic induration , sarcoidosis , thrombocytopenia , atherosclerosisand antiphospholipid syndrome .
Norovirus
This computer virus is tie in to tum flu ( viral gastroenteritis ) that has symptoms ofnausea , vomiting , diarrheaand belly pain in the neck with low - class fever , muscularity pain and head ache . Norovirus is associated with the development ofCrohn ’s disease .
Borrelia Burgdorfeii
Thistick bornespirochete is responsible for Lyme disease in the US and 60 % untreated cases may developarthritisand advance to inveterate Lyme arthritis that may be antibiotic immune and even develop Central Nervous System complications .
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