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What is Actinic Prurigo?
Actinic Prurigo is a status characterized by episodes of severe itch in area of the eubstance expose to direct sunlight . Primarily , Actinic Prurigo causes rashes that are extremely itchy . It also causes small erythematous papules on the skin surface . These papules may crust or ooze at times . The most common field where it can be insure is the human face , lip , cheek , neck , arms , and chest . Sometimes , Actinic Prurigo may also cause severe irritation in the centre , especially in live weather conditions.[1,2,3 ]
There have also been cases of Actinic Prurigo where body parts that have not been exposed to sun have also been affect . Actinic Prurigo is seen mainly in females and that too young lady who are about 10 years of age even though anyone can get it at any eld . There is a strong genetic link to the development of Actinic Prurigo . It is mainly seen in people living in Central , North , and South America.[1,2,3 ]
There is no cure for Actinic Prurigo but symptoms can be make do . The management start with maximum avoidance of verbatim sun . If that is not potential then right aid should be lease to protect the body parts that are exposed directly to sun . Additionally , topical corticosteroids and anti - itch creams are also quite effective for flair - ups of Actinic Prurigo.[1,2,3 ]
What Causes Actinic Prurigo?
The chief cause of Actinic Prurigo is not very unclouded . However , experts conceive there is a unattackable familial link to the ontogeny of this precondition pointing it towards being an autoimmune upset . Actinic Prurigo is extremely rare in the United States but is seen ordinarily in the South and Central American Carry Nation due to the vividness of the heat in these regions.[1,2 ]
There is no gender bias for Actinic Prurigo but is realize more in female than male person . It can rise at any age but usually is seen in female child around 10 years of age . Some studies refer that Actinic Prurigo is find out more in ironical and warm climatic conditions.[1,2 ]
What are the Symptoms of Actinic Prurigo?
The symptom onset of Actinic Prurigo is begins generally in the spring as the strength of sunlight increment by then and citizenry expend more time out in the sunlight after the tough winter . The primary presenting symptom of a person with Actinic Prurigo is hard itchy erythematous rash in the area exposed to the sun like the face , neck opening , cheek , and arms.[1,2 ]
In some case , even the unexposed areas of the body may get the Hellenic rash as seen with Actinic Prurigo . There may also be inspissate of the skin and mark . Another telltale sign of Actinic Prurigo is the bearing of actinic cheilitis . This is a condition characterized by inflammation of the brim after exuberant sunlight exposure . In fact , this may be the only signal present in a patient with Actinic Prurigo.[1,2 ]
How is Actinic Prurigo Treated?
Mild cases of Actinic Prurigo can be easily cope by annul sunlight exposure . If the person has to go out in the Dominicus then protecting the piece of the body give away to Lord’s Day by direction of sunscreen and sunglasses , wear protective clothing , and going into tone as much as possible is recommended . Wearing wide - brim hats is also quite effective in avoid unmediated sunlight on the face.[1,2 ]
For more severe cases , topical corticosteroids and antihistamines have been shown to be efficacious in finagle the symptom of Actinic Prurigo . For more chronic and severe cases , the patient role will require aggressive discussion in the descriptor of antimalarials , tetracycline , and systemic steroids . Thalidomide has shew first-class effectiveness in the treatment of Actinic Prurigo when other medications have been prove to be ineffective.[1,2 ]
However , this handling approach has a side burden profile which includes peripheral neuropathy and teratogenicity , both of which are major side effects and caution needs to be keep while taking this medication . Additionally , this treatment is not urge for pregnant female or female who are trying to conceive . Females of procreative age are recommend to utilize contraceptives while on the thalidomide therapy for treatment of Actinic Prurigo . hoi polloi on this therapy should be closely monitored for any signs ofperipheral neuropathy.[1,2 ]
Alternatively , immunosuppressive agents like cyclosporine have also been found to be good in managing the symptoms of Actinic Prurigo . Another treatment that has been extremely successful in cover the skin changes due to Actinic Prurigo is Photochemotherapy.[1,2 ]
In conclusion , Actinic Prurigo is a stipulation that tends to go back every time the body is queer to direct sunshine . There is no known cause for this consideration . Minor cases of Actinic Prurigo can be treated with just sun avoidance . However , chronic and refractory forms will postulate handling with immunosuppressants like cyclosporine and thalidomide.[1,2,3 ]
Caution needs to be maintain when being on thalidomide therapy as it has significant side effect visibility of peripheral neuropathy for which the patient role should be tight monitor . It is also recommended that pregnant females not use this medication and females of reproducing age use contraceptive when on this medication.[1,2,3 ]
It has also been picture that some citizenry specially girls who have not attained puberty outgrow this stipulation and by the metre they become grownup there is complete resolving power of Actinic Prurigo.[1,2,3 ]
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