What is Esthesioneuroblastoma or Olfactory Neuroblastoma?
Esthesioneuroblastoma or Olfactory Neuroblastoma , is an exceedingly rare mannikin of the Head and Neck Cancers . We can also call this cancer the Cancer of the Sense of Smell since it greatly move the soul sense of smell and predilection . One very crucial thing that has to be mention about esthesioneuroblastoma or olfactory neuroblastoma type of rare cancer is that it is not related at all to any other neuroblastoma malignant tumour found elsewhere in the body .
Causes of Esthesioneuroblastoma or Olfactory Neuroblastoma
You have in all likelihood reason from the very fact that esthesioneuroblastoma or olfactory neuroblastoma is very rare and because of that its cause is strange . If you had thought that way , you were correct because the main cause of esthesioneuroblastoma or olfactory neuroblastoma is rather unidentified . Moreover , the drive of this malignant tumor is one of the biggest aesculapian mysteries .
It is so rare that the aesculapian researchers and pathologists did not take up a luck of their prison term investigate the suit of esthesioneuroblastoma or olfactory neuroblastoma . However , there are certain possible causes of this Crab that were mentioned in the aesculapian literature .
It is hypothesize that the independent causes of esthesioneuroblastoma or olfactory neuroblastoma are transmitted and environmental factors . multitude who had a family member with any Head and Neck cancer are at the greater peril of develop this malignant disease . Smokers are also at risk of developing Olfactory Neuroblastoma .
What confuses aesculapian professionals is from which cells does esthesioneuroblastoma or olfactory neuroblastoma originate from . However , the most unwashed cells whose abnormal growth have olfactory neuroblastoma are the olfactive sensory cell which are found in the olfactory epithelium .
Symptoms of Esthesioneuroblastoma or Olfactory Neuroblastoma
As is the principle for all of the malignant diseases , the symptoms of esthesioneuroblastoma or olfactory neuroblastoma greatly depend on the extent and stage of that tumour . woefully , this subtle disease does not show any signs and symptom in its beginning stages .
The two tell - tale symptoms that might make your doctor suspicious of you having esthesioneuroblastoma or olfactory neuroblastoma are epistaxis and pinched obstruction . We can define pinched obstruction as the inability to emit through each of the nostril . Epistaxis is the aesculapian term for nose bleeding . Bleeding very often from your nozzle and complaining about it to your medical doctor might have it conceive that you have esthesioneuroblastoma or olfactory neuroblastoma .
The most common symptoms of esthesioneuroblastoma or olfactory neuroblastoma are :
All of the symptom above are relate to the extension of the esthesioneuroblastoma or olfactory neuroblastoma neoplasm . Sadly , most of the symptoms of the underlie neuroblastoma resemble benignant seditious processes and thus an enormous delay is often made with diagnose this tumor . In most of the medical field , the intermediate time from the onset of symptom to diagnose esthesioneuroblastoma or olfactory neuroblastoma is six to twelve months . Because of this fact , most of the patient role with this cancer are name when their tumor had invaded the surround organs and had entered the lymphatic system .
Tests to Diagnose Esthesioneuroblastoma or Olfactory Neuroblastoma
If your family physician defendant that you might have esthesioneuroblastoma or olfactory neuroblastoma , he / she would most probably commit you to an ENT specialist . If any ENT specialiser you were referred to suspects that you might have the rarefied cancer esthesioneuroblastoma or olfactory neuroblastoma , he / she will first order nasal endoscopy .
Nasal endoscopy is an invasive medical procedure . A small tube with a camera on its top will be insert in your nose . The mortal who will perform this procedure will inclose the tube with camera all the way through your nose to yoursinuses . If this function confirms the comportment of any lesion within your upper nasal pit that resemble esthesioneuroblastoma or olfactory neuroblastoma , a procedure called intranasal biopsy will be ordered . If the biopsy results test positive for Esthesioneuroblastoma , two radiological test will be ordered which areCT ScanandMRI scan .
A CT CAT scan is postulate to appraise at what stage esthesioneuroblastoma or olfactory neuroblastoma is at . Also , CT scan evidence the signs of cribriform plate erosion or skull base bone erosion which are both lawsuit by esthesioneuroblastoma or olfactory neuroblastoma .
MRI scan is needed to better delineate intracranial , intraorbital , and sinonasal telephone extension of esthesioneuroblastoma or olfactory neuroblastoma . Also , patients diagnose with esthesioneuroblastoma or olfactory neuroblastoma should call oculist since this term usually causes underage or major terms to the eye .
Staging of Esthesioneuroblastoma or Olfactory Neuroblastoma
There is no prescribed staging organization for esthesioneuroblastoma or olfactory neuroblastoma . However , the Kadish clinical theatrical production system is used to describe the staging . According to Kadish clinical staging system , there are three microscope stage of esthesioneuroblastoma or olfactory neuroblastoma which are :
stagecoach A esthesioneuroblastoma or olfactory neuroblastoma is typically confined to the nasal cavity . phase B esthesioneuroblastoma had go to the paranasal sinuses . Stage C of ENB is described as a tumor that had extended the paranasal sinuses .
Treatment for Esthesioneuroblastoma or Olfactory Neuroblastoma
The surgical operation of esthesioneuroblastoma or olfactory neuroblastoma is a preferred treatment selection for do by this malignant disease . After the successful surgery of esthesioneuroblastoma or olfactory neuroblastoma , a radiation sickness therapy is performed . radiation sickness therapies used for treating this disease are Gamma Knife surgery and IMRT ( Intensity Modulated Radiation Therapy ) .
For patients with a Kadish stagecoach C esthesioneuroblastoma or olfactory neuroblastoma , chemotherapy is prescribed . Doxorubicin , Cyclophosphamide , Vincristine , Etoposide , and Cisplatin are the chemotherapeutic agents used for the treatment .
Survival Rate for Esthesioneuroblastoma or Olfactory Neuroblastoma
The survival of the fittest rate for esthesioneuroblastoma or olfactory neuroblastoma greatly depends on the point this malignant disease had reach out . These are the 5 - year survival of the fittest rate for the patients name with esthesioneuroblastoma or olfactory neuroblastoma according to this disease ’s stage :
Recovery Period/Healing Time for Esthesioneuroblastoma or Olfactory Neuroblastoma
patient role who had operating theatre of their esthesioneuroblastoma or olfactory neuroblastoma cancer usually stay at the hospital several Clarence Day after the operating room . However , these patient will most in all probability lose their sense of feel .
Also , at least for several week , the patients who had esthesioneuroblastoma or olfactive neuroblastoma OR would have to breathe through their mouth . Your doctor will provide the recovery catamenia / healing time free-base on your particular case .
Prevention of Esthesioneuroblastoma or Olfactory Neuroblastoma
Although no prevention method acting regarding any cancer has been proved to greatly prevent it from develop , the best prevention method acting in terms of prevent esthesioneuroblastoma or olfactory neuroblastoma is cease smoke .
Annual visit to the ENT special are also the near agency to diagnose ahead of time or prevent the growth of esthesioneuroblastoma or olfactory neuroblastoma .
Risk Factors for Esthesioneuroblastoma or Olfactory Neuroblastoma
The risk factors for developing esthesioneuroblastoma or olfactory neuroblastoma are either inherited or environmental . The genetic risk factor for acquire the malignant esthesioneuroblastoma or olfactory neuroblastoma is a family history or any other Neuroblastoma .
The environmental peril factors for rise esthesioneuroblastoma or olfactory neuroblastoma is being exposed incessantly to polluted air travel and high doses of radiation . Also , smoking for a farsighted period of time also personate a jeopardy for developing this circumstance .
Prognosis/Outlook for Esthesioneuroblastoma or Olfactory Neuroblastoma
Luckily , esthesioneuroblastoma or olfactory neuroblastoma tumors are less aggressive than the other type of paranasal sinus carcinoma and sinus carcinoma . However , if this case of Crab is not name at its early stages , it spreads to the other parts of the body such as the brain and neck opening . Then the forecast of esthesioneuroblastoma or olfactory neuroblastoma is fatal .
Coping with Esthesioneuroblastoma or Olfactory Neuroblastoma
The keep of the family of a patient name with esthesioneuroblastoma or olfactory neuroblastoma is the best apprehend method acting for that patient . Patients diagnosed with the former and curable level of this disease should be admitted to a psychologist for treat the initial shock of hearing they have cancer . Palliative guardianship is the recommend coping method for the patients with esthesioneuroblastoma or olfactory neuroblastoma in terminal stages .
