The abnormal high stratum of Homocysteine ( when the level ascend above 15 µmol / L ) leads to abnormality in the human body and a medical crisis know as Hyperhomocysteinemia . The high level of homocysteine is led to due to deficiency of vitamins like B6 , folic acid or B9 or B9 since in several chemical substance reaction necessitate homocysteine . If your vitamin B6 , B9 and B12 breathing in is append or increase , such a wellness harm offspring can be check and get by . The outcomes of these vitamin being more in amount in your body would n’t lead to any change .
What is Hyperhomocysteinemia?
Homocysteine is release as a result of the amino acid breakdown during the process of protein metabolism . When the amount of it increase , the physical structure gets prostrate to diseases like risks of having a sum attack or a apoplexy . Also the same can create a plague formation and damage the arterial walls . Further , the homocysteine can clot the pedigree and by play on the rip platelets . Whether the higher level of homocysteine causes severe cardio vascular disease is yet to be confirmed . Another risk that one gets endured to is to be having double the risk of developingAlzheimer ’s disease .
If you are a even consumer of folic food , protein , fruits and green leafy vegetables , the blood level of homocysteine in you will be more . It shall be neutralize by the B6 , B9 and B12 vitamins you will be taking in everyday in your diet in the form of the above mentioned nutrient .
Homocysteine can also be produce in the body from another amino acid ; methionine . Methionine is the provider for methyl group . Methyl radical ’s sherd contains one carbon paper and 3 atomic number 1 atoms . donate a methyl radical group micturate methionine convert into homocysteine . In the similar fashion , homocysteine find different methyl group groups from folic loony toons or vitamin B6 and convert back to methionine .
The relationship between levels of homocysteine in your blood and risk of heart disease is still controversial .
A large study was done in UK in 2012 . There UK debated about the fact that homocysteine acts as a risk element for sum disease . The research further showed that the 116000 people were genetically psychoanalyse for variation in a gene that cue homocysteine formation . The bailiwick also read that the mutation itself acted as a case for the rise of homocysteine , by 20 % . These study participants who were touch on showed risks of having a heart and soul disease . The account was print in PLoS Medicine in February , 2012 .
Another published field in New England Journal of Medicine in April , 2006 showed that fair sex who are affected by heart disease have raise homocysteine and are prone to death four time more than the women with normal levels . It is still undecipherable if the high floor of homocysteine caused the heart diseases or the heart diseases led to the rise of high level of homocysteine .
Causes of Hyperhomocysteinemia
The main suit for ayperhomocysteinemia or elevated stage of homocysteine in blood is the deficient uptake of vitamin vitamin B group . The other cause of hyperhomocysteinemia is genetical factor which settle the folic dot intake in our body and therefore can lead to rarified homocysteine . In such a case , you must increase your folic Lucy in the sky with diamonds intake to more than RDA of 400 microgram .
Signs and Symptoms of Hyperhomocysteinemia
There are no verbatim signs and symptom of Hyperhomocysteinemia but a figure of disease are related to the eminent levels of homocysteine in blood .
Diagnosis of Hyperhomocysteinemia
The diagnosing of hyperhomocysteinemia is done by stemma tests . With the assistance of blood tests you could check the stage of homocysteine within your physical structure . If you have a family history of not many risk cistron but heart disease then the physicians might advise you to do the test to check up for high cholesterol and high-pitched line of descent pressure level along with the blood tryout for homocysteine . These psychometric test shape the degree of homocysteine in your body is not done everywhere . These tests are rarely uncommitted . The proper level of homocysteine which is harmless for the body is 4.4 . and 10.8 micromoles per cubic decimeter of blood .
Treatment for Hyperhomocysteinemia
Other than increase the intake of vitamin B in your dieting , there is no right and prescribed mode to treat the high-pitched level of homocysteine aka Hyperhomocysteinemia in your body . You must increase the intake of green leafy vegetable , whole grain based food for increasing vitamin b group in your body . Studies which can prove that lower degree of homocysteine can bring down the risk of heart diseases are yet to be make out . It can also be that people did n’t research about it in great detail or they failed to bring down the horizontal surface of homocysteine .
You will always find the doctor involve you to wipe out foods that have a gamy folic acid . The pteroylmonoglutamic acid ( food hold folic acid ) like green , leafy vegetable , orange juices and bean redeem a immense amount of vitamin B complex chemical group in your body which will bring down the level of homocysteine in your blood . Doctors also suggest taking multivitamin tablets which will sum up micrograms of more folic acid than your usual content . This is take by people as a auxiliary physical body to their dieting and Doctor pertain this as good insurance policy . For reducing stress , the doctors might require you to drill breathing exercises . you could also modernize the habit of meditating or doing yoga regularly . If you may decrease your inlet of animate being protein and sharpen more on proteins like that in Pisces the Fishes or bean , whole soy products and dairy then the homocysteine level may go down . Doctors also intimate to nullify inflammatory food , and bring don your protein intake up to 120 gramme daily .
All the above mentioned ways assist in treating Hyperhomocysteinemia .
