What is Polycythemia Vera?
Polycythemia Vera ( PV ) is a eccentric of chronic Crab of the blood , which set forth in the off-white marrow which is the delicate center of the bone where the production of new parentage cell takes place . In persons involve by polycythemia vera , there is undue production of scarlet blood cells , and other cells , such as platelets and ashen bloodline cells in thebone marrow , which bring in the blood very thickheaded in consistence result in increase likelihood of a person give blood coagulum , heart attack or a fortuity . Polycythemia vera is a rare condition , which develops slowly , often over a period of many year . With proper discussion and forethought , patients tolerate from Polycythemia vera can live for many class ; however , if treatment is not started , then it can become a life endanger experimental condition . There is also a risk of development of other more fatal bloodline cancers , such as acute leucaemia ormyelofibrosis . Polycythemia vera tends to develop in someone who are 60 years of age or more ; however , people of any historic period can be touch by it . man are more susceptible to it than cleaning woman . Patient may experience some warning signs , such as weakness , tiredness and dizziness . Polycythemia vera often is discovered during a routine blood tryout where the increased reckoning of blood line cellphone is let on .
There is no remedy for Polycythemia vera . Treatment for Polycythemia vera depends on the patient role ’s eld , general health and each someone ’s case . handling focalize on decreasing the blood cell count and alleviating the symptoms . If the affected role is not having lot of symptom , then he / she may only be observed on a even basis without any discourse being done .
Causes & Risk Factors of Polycythemia Vera
Polycythemia vera is not a contagious disease . It does not buy the farm from one person to another like acommon frigidity . It occur when there is a problem in the cistron known as JAK2 , which is creditworthy for keeping a hindrance on the overweening production of rip cells . Rarely , this faulty gene can be hap to the children from the parent .
There are three types of blood cells made by the off-white marrow , red blood cells , white blood line cells and platelet . The red blood cellular phone are responsible for carry oxygen , the white line of descent cubicle fight infections , and the platelets are responsible for clotting the descent so haemorrhage is stopped . In majority of case , there is excessive production of ruby blood cells in polycythemia vera , however , there can also be exuberant production of platelets and white parentage cells .
The risk of Polycythemia Vera is more as a person years . Individuals over the eld of 60 are at an increased risk for have this condition . Men are more likely to develop Polycythemia Vera than women .
Signs & Symptoms of Polycythemia Vera
ab initio , the patient may not experience any symptom of polycythemia vera and the disease gets discover during routine blood tests . If patient does not seek discourse , then the exuberant red pedigree mobile phone increase the risk of rakehell coagulum , which in turn of events blockade the roue circulation . This result to increase in the risk for stroke andheart attackalong with causingchest pain(angina ) .
Common symptom of Polycythemia Vera include :
Diagnosis of Polycythemia Vera
Treatment for Polycythemia Vera
There is no cure for Polycythemia Vera . Treatment for it depends on patient to patient and is aimed at cut back the blood jail cell count , relieve the signs and symptoms and trying to prevent complications from polycythemia vera . If the patient is not experiencing any symptoms , then treatment may not be set out and the patient is only monitor or observed on a regular groundwork . Treatment for Polycythemia Vera consists of :
Lifestyle Modifications for Polycythemia Vera
Prognosis & Life Expectancy of Polycythemia Vera
There is no therapeutic for Polycythemia Vera ; however , with right treatment , patient can endure for many years with this disease and are capable to lead an alive aliveness . It should also be take over in idea that each patient has unlike grade of disease and the prognosis can change from patient to patient role . In rarified case , Polycythemia Vera can lead to other fatal profligate Crab , such as myelofibrosis or acute accent leucaemia . About 15 % of patients put up from PV may develop a serious and advance stage of polycythemia vera , which is known as myelofibrosis . In this condition , bone heart transplantation may be expect . With even treatments and monitoring , patient can go with Polycythemia Vera for around 35 to 40 years . It is important to essay financial backing of household and friends and seek to keep a irrefutable attitude to fight this disease .
