What are Statins?
Statins are a stratum of drugs that are most commonly dictate to help lower high horizontal surface of cholesterol . These medicament target the levels of LDL cholesterol , while at the same time influence towards boosting the levels of HDL cholesterol in the body . When you have high levels of LDL cholesterol , it can start accumulating on the arterial walls . This causes a simplification in pedigree stream through the arteries , thus increasing the risk of heart disease , coronary artery disease , solidus , gist attack , and other related to diseases .
lipid-lowering medicine help lower the levels of LDL cholesterol by inhibiting an enzyme that the dead body requires for produce cholesterin . lipid-lowering medication also help disregard down the memorial tablet ( made up of cholesterol ) that has already build up in your arteries . In this way , statins reduce the risk of many heart - related diseases and a stroke or heart attack .
Why Should You Take Statins At Night?
Most doctors recommend that you take statins at nighttime . This is because the body ’s cholesterin - invent enzyme is most alive during the nighttime , which makes the statins more effectual when contain at night . what is more , the half - life of statins , or the amount of clip it takes for half of the dose of the statin to go out the body , is not too long . The half - lives of some statins are even less than six hours . This is why statins are most efficient when lease at Nox .
For example , simvastatin is a good example of a statin that works most expeditiously if it ’s taken in the eventide . Studies have shown that there is a higher reduction in LDL cholesterol levels when simvastatin is taken at dark , when compared to this statin taken in the morning time .
Another statin , Mevacor , wreak easily when adopt with dinner party . However , if you are taking the extend - release version of this statin , Altoprev , then you want to take that at bedtime .
Fluvastatin , another commonly dictate statin , has a half - life of just three hour . This is why fluvastatin is also the most effective when taken at night .
Types of Statins
There are many types of statin drug available in both branded and generic form . Some of the commonly prescribe lipid-lowering medication include : rosuvastatin ( Crestor ) , lovastatin ( Altoprev , Mevacor ) , simvastatin ( Zocor ) , pitavastatin ( Livalo ) , Pravachol ( Pravachol ) , fluvastatin ( Lescol XL ) and atorvastatin ( Lipitor ) .
Most of these statin medications need to be taken once every 24 hours , and sometimes , calculate on the dosage and the particular statin , you might even want to take it doubly in a twenty-four hours . Some statins are effective when lead with food for thought , while some statin are most good when they are taken at night .
Are There Statins That Can Be Taken In The Morning?
Not all lipid-lowering medicine work best when submit at dark . There are some new lipid-lowering medicine that work equally efficient when take in in the morning . Studies have shown that the HMG - CoA reductase inhibitors , like rosuvastatin and atorvastatin , are the newer statin drug that are more in effect and powerful than the older statins . The new statins also have half - lives of nearly 14 hour , which is why you could take them either in the first light or at night .
For example , the extend - release variant of fluvastatin , Lescol XL , can be make at any time of the daytime .
Common Side Effects of Statins
While statins are highly efficacious at see to it your cholesterol grade , they are not without their percentage of risk . Some of the coarse side effects of lipid-lowering medication admit : nausea , headaches , muscle andjoint pain .
Some of the serious risks associated with lipid-lowering medicine also include legal injury to your muscle , liver and kidneys . Additionally , if you have type 2 diabetes , then statins are probable to increase your levels of ancestry glucose .
Switching to another statin if you are experiencing side consequence can help oneself sometimes . Talk to your doctor if you are experiencing any side effects from your statin .
Important Facts You Need To Know About Statins
Your doctor should be aware of all your personal conditions and medical issues , such as allergies before they can dictate you the best statin for your private caseful . Do make certain that you investigate your Dr. whether the statin has to be taken at a specific metre of day or if it has to be taken with solid food .
If your doctor allege that you could take the statin at any time , then also you should select to maintain the same time each solar day . This is because statins work best when they are taken at the same time every day . Make it a part of your act so that you do n’t forget to take it .
Also keep in nous that when you are taking statins , you could not salute Citrus paradisi succus or wipe out Citrus paradisi . Grapefruit interacts with a statin and induce the medication to persist inside your body for a much longer period of clip . This can cause a build up - up of statin inside the body , increase the peril of muscle breakdown , kidney damage or kidney unsuccessful person and liver equipment casualty .
Statins can also interact with other medications , which is why it is so important to inform your Doctor of the Church about all the other medications you are take . This also includes over - the - counter medications , appurtenance , prescription medicine drugs , and any herbal medicament as well .
Conclusion
lipid-lowering medicine are the most effective medication for lower increase cholesterin grade . Most statins knead best when taken in the late eve or at night just before going to bed . The timing of taking the drug is authoritative because your organic structure construct more cholesterol during the night . Statins take around four to six weeks to take off showing results and after six to eight weeks , your Doctor of the Church will plausibly again check your LDL cholesterol levels to see if your medicine is play or not . Keep following the instructions of the statins cautiously to achieve the best solvent from these cholesterol - lowering drugs .
